This select list of publications may be accessed online at PUBMED

Title Author Journal Date PubMed ID
Alterations in intestinal permeability Arrieta M.C., et al. Gut Oct-2006 16966705
Mucosal barrier defects in irritable bowel syndrome. Who left the door open? Barbara G Am J Gastroenterol June-2006 16771952
Mechanisms of disease: the role of intestinal barrier function in the pathogenesis of gastrointestinal autoimmune diseases Fasano A., et al. Nat Clin Pract Gastroenterol Hepatol Sep-2005 16265432
Changes in intestinal morphology and permeability in the biobreeding rat before the onset of type 1 diabetes Neu J., et al. J Pediatr Gastroenterol Nutr May-2005 15861021
A porous defense: the leaky epithelial barrier in intestinal disease Clayburgh D.R., et al. Lab Invest March-2004 14767487
Ultrastructural mucosal alterations and increased intestinal permeability in non-celiac, type I diabetic patients Secondulfo M., et al. Dig Liver Dis Jan-2004 14971814
Increased intestinal permeability as a cause of fluctuating postprandial blood glucose levels in Type 1 diabetic patients Damci T., et al. Eur J Clin Invest May-2003 12713453
Early effects of gliadin on enterocyte intracellular signalling involved in intestinal barrier function Clemente M.G., et al. Gut Feb-2003 12524403
Intestinal barrier function Baumgart D.C., et al. Curr Opin Clin Nutr Metab Care Nov-2002 12394645
Intestinal permeation and gastrointestinal disease DeMeo M.T., et al. J Clin Gastroenterol Apr-2002 11907349
Abnormal intestinal permeability predicts relapse in inactive Crohn disease Arnott I.D., et al. Scand J Gastroenterol Nov-2000 11145287
Increased gastrointestinal permeability is an early lesion in the spontaneously diabetic BB rat Meddings J.B., et al. Am J Physiol Apr-1999 10198339
Title Author Journal Date PubMed ID
Inflammatory bowel disease: is it really just another break in the wall? Weber C.R., et al. Gut Jan-2007 17172583
Evolving knowledge and therapy of inflammatory bowel disease Korzenik J.R., et al. Nat Rev Drug Discov Mar-2006 16518373
Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease Blair S.A., et al. Lab Invest Feb-2006 16402035
Wheat protein-induced proinflammatory T helper 1 bias in mesenteric lymph nodes of young diabetes-prone rats Chakir H., et al. Diabetologia Aug-2005 16003532
Dual sugar gut-permeability testing on blood drop in animal models Katouzian F., et al. Clin Chim Acta Feb-2005 15653114
Role of the intestinal tight junction modulator zonulin in the pathogenesis of type I diabetes in BB diabetic-prone rats Watts T., et al. Proc Natl Acad Sci U S A Feb-2005 15710870
Insulin-dependent diabetes and gut dysfunction: the BB rat model Malaisse W.J., et al. Horm Metab Res Sep-2004 15486808
Zonula occludens toxin acts
as an adjuvant through different mucosal routes and induces protective immune responses
Marinaro M., et al. Infect Immun Apr-2003 12654806
Zonula occludens toxin increases the permeability of molecular weight markers and chemotherapeutic agents across the bovine brain microvessel endothelial cells Karyekar C.S., et al. J Pharm Sci Feb-2003 12532391
Zonula occludens toxin (Zot) interferes with the induction of nasal tolerance to gliadin Rossi M., et al. Immunology Letters May-2002 11947928
Increased gastrointestinal permeability is an early lesion in the spontaneously diabetic BB rat Meddings J.B., et al. Am J Physiol Apr-1999 10198339
Modulation of intestinal tight junctions by Zonula occludens toxin permits enteral administration of insulin and other macromolecules in an animal model Fasano A., et al. J Clin Invest Mar-1997 9077522
Food-induced type 1 diabetes in the BB rat Scott F.W., et al. Diabetes Metab Rev Dec-1996 9013075
Title Author Journal Date PubMed ID
Increased intestinal permeability precedes clinical onset of type 1 diabetes Bosi E., et al. Diabetologia Dec-2006 17028899
Inflammatory bowel disease and the apical junctional complex Bruewer M., et al. Ann N Y Acad Sci Aug-2006 17057204
Zonulin upregulation is associated with increased gut permeability in subjects with type 1 diabetes and their relatives Sapone A., et al. Diabetes May-2006 16644703
tate of the art: IBD therapy and clinical trials in IBD Isaacs K.L., et al. Inflamm Bowel Dis Nov-2005 16254481
Risk of celiac disease autoimmunity and timing of gluten introduction in the diet of infants at increased risk of disease Norris J.M., et al. JAMA May-2005 15900004
Association of celiac disease and intestinal lymphomas and other cancers Catassi C., et al. Gastroenterology Apr-2005 15825131
Clinical features and diagnosis of celiac disease Dewar D.H., et al. Gastroenterology Apr-2005 15825122
Celiac disease in patients with an affected member, type 1 diabetes, iron-deficiency, or osteoporosis? Murray J.A. Gastroenterology Apr-2005 15825127
National Institutes of Health Consensus Development Conference Statement on Celiac Disease, June 28-30, 2004 James S.P. Gastroenterology Apr-2005 15825115
The G.U.T. of gut Bjarnason I., et al. Scand J Gastroenterol Sep-2004 15513377
Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences Loftus E.V. Gastroenterology May-2004 15168363
Timing of initial cereal exposure in infancy and risk of islet autoimmunity Norris J.M., et al. JAMA Oct-2003 14519705
Early infant feeding and risk of developing type 1 diabetes-associated autoantibodies Ziegler A.G., et al. JAMA Oct-2003 14519706
Celiac disease--how to handle a clinical chameleon Fasano A. NEJM Jun-2003 12815143
Title Author Journal Date PubMed ID
A prospective, double-blind, placebo-controlled trial to establish a safe gluten threshold for patients with celiac disease Catassi C., et al. Am J Clin Nutr Jan-2007 17209192
Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines Drago S., et al. Scand J Gastroenterol Apr-2006 16635908
Integrating theories of the etiology of Crohn's disease. On the etiology of Crohn's disease: questioning the hypotheses. Chamberlin W.M., et al. Med Sci Monit Feb-2006 16449960
Gliadin stimulation of murine macrophage inflammatory gene expression and intestinal permeability are MyD88-dependent: role of the innate immune response in Celiac Thomas K.E., et al. J Immunol Feb-2006 16456012
Clinical features and diagnosis of celiac disease Dewar D.H., et al. Gastroenterology Apr-2005 15825122
The safe threshold for gluten contamination in gluten-free products. Can trace amounts be accepted in the treatment of coeliac disease? Collin P., et al. Aliment Pharmacol Ther Jun-2004 15191509
Sourdough bread made from wheat and nontoxic flours and started with selected lactobacilli is tolerated in celiac sprue patients Di Cagno R., et al. Appl Environ Microbiol Feb-2004 14766592
Environmental factors in the etiology of type 1 diabetes Akerblom H.K., et al. Am J Med Genet May-2002 12116173
Environmental triggers of type 1 diabetes Couper J.J. J Paediatr Child Health Jun-2001 11474705
Zonula occludens toxin structure-function analysis. Identification of the fragment biologically active on tight junctions and of the zonulin receptor binding domain Di Pierro M., et al. J Biol Chem Jun-2001 11278543
Current concepts of celiac disease pathogenesis Schuppan D. Gastroenterology Jul-2000 10889174
Vibrio cholerae produces a second enterotoxin, which affects intestinal tight junctions Fasano A., et al. Proc Natl Acad Sci U S A Jun-1991 2052603
Dietary proteins as environmental modifiers of type 1 diabetes mellitus Lefebvre D.E., et al. Annu Rev Nutr Jun-1905 16848704
Regulation of intercellular tight junctions by zonula occludens toxin and its eukaryotic analogue zonulin Fasano A. Ann N Y Acad Sci Jun-1905 11193578