The following is a select list of publications. These publications can be accessed online at PUBMED
INN-202
| Title |
Author |
Journal |
Date |
PubMed ID |
| Alterations in intestinal permeability |
Arrieta M.C., et al. |
Gut |
Oct-2006 |
16966705 |
| Mucosal barrier defects in irritable bowel syndrome. Who left the door open? |
Barbara G |
Am J Gastroenterol |
June-2006 |
16771952 |
| Mechanisms of disease: the role of intestinal barrier function in the pathogenesis of gastrointestinal autoimmune diseases |
Fasano A., et al. |
Nat Clin Pract Gastroenterol Hepatol |
Sep-2005 |
16265432 |
| Changes in intestinal morphology and permeability in the biobreeding rat before the onset of type 1 diabetes |
Neu J., et al. |
J Pediatr Gastroenterol Nutr |
May-2005 |
15861021 |
| A porous defense: the leaky epithelial barrier in intestinal disease |
Clayburgh D.R., et al. |
Lab Invest |
March-2004 |
14767487 |
| Ultrastructural mucosal alterations and increased intestinal permeability in non-celiac, type I diabetic patients |
Secondulfo M., et al. |
Dig Liver Dis |
Jan-2004 |
14971814 |
| Increased intestinal permeability as a cause of fluctuating postprandial blood glucose levels in Type 1 diabetic patients |
Damci T., et al. |
Eur J Clin Invest |
May-2003 |
12713453 |
| Early effects of gliadin on enterocyte intracellular signalling involved in intestinal barrier function |
Clemente M.G., et al. |
Gut |
Feb-2003 |
12524403 |
| Intestinal barrier function |
Baumgart D.C., et al. |
Curr Opin Clin Nutr Metab Care |
Nov-2002 |
12394645 |
| Intestinal permeation and gastrointestinal disease |
DeMeo M.T., et al. |
J Clin Gastroenterol |
Apr-2002 |
11907349 |
| Abnormal intestinal permeability predicts relapse in inactive Crohn disease |
Arnott I.D., et al. |
Scand J Gastroenterol |
Nov-2000 |
11145287 |
| Increased gastrointestinal permeability is an early lesion in the spontaneously diabetic BB rat |
Meddings J.B., et al. |
Am J Physiol |
Apr-1999 |
10198339 |
| Title |
Author |
Journal |
Date |
PubMed ID |
| Inflammatory bowel disease: is it really just another break in the wall? |
Weber C.R., et al. |
Gut |
Jan-2007 |
17172583 |
| Evolving knowledge and therapy of inflammatory bowel disease |
Korzenik J.R., et al. |
Nat Rev Drug Discov |
Mar-2006 |
16518373 |
| Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease |
Blair S.A., et al. |
Lab Invest |
Feb-2006 |
16402035 |
| Wheat protein-induced proinflammatory T helper 1 bias in mesenteric lymph nodes of young diabetes-prone rats |
Chakir H., et al. |
Diabetologia |
Aug-2005 |
16003532 |
| Dual sugar gut-permeability testing on blood drop in animal models |
Katouzian F., et al. |
Clin Chim Acta |
Feb-2005 |
15653114 |
| Role of the intestinal tight junction modulator zonulin in the pathogenesis of type I diabetes in BB diabetic-prone rats |
Watts T., et al. |
Proc Natl Acad Sci U S A |
Feb-2005 |
15710870 |
| Insulin-dependent diabetes and gut dysfunction: the BB rat model |
Malaisse W.J., et al. |
Horm Metab Res |
Sep-2004 |
15486808 |
Zonula occludens toxin acts
as an adjuvant through different mucosal routes and induces protective immune responses |
Marinaro M., et al. |
Infect Immun |
Apr-2003 |
12654806 |
| Zonula occludens toxin increases the permeability of molecular weight markers and chemotherapeutic agents across the bovine brain microvessel endothelial cells |
Karyekar C.S., et al. |
J Pharm Sci |
Feb-2003 |
12532391 |
| Zonula occludens toxin (Zot) interferes with the induction of nasal tolerance to gliadin |
Rossi M., et al. |
Immunology Letters |
May-2002 |
11947928 |
| Increased gastrointestinal permeability is an early lesion in the spontaneously diabetic BB rat |
Meddings J.B., et al. |
Am J Physiol |
Apr-1999 |
10198339 |
| Modulation of intestinal tight junctions by Zonula occludens toxin permits enteral administration of insulin and other macromolecules in an animal model |
Fasano A., et al. |
J Clin Invest |
Mar-1997 |
9077522 |
| Food-induced type 1 diabetes in the BB rat |
Scott F.W., et al. |
Diabetes Metab Rev |
Dec-1996 |
9013075 |
| Title |
Author |
Journal |
Date |
PubMed ID |
| Increased intestinal permeability precedes clinical onset of type 1 diabetes |
Bosi E., et al. |
Diabetologia |
Dec-2006 |
17028899 |
| Inflammatory bowel disease and the apical junctional complex |
Bruewer M., et al. |
Ann N Y Acad Sci |
Aug-2006 |
17057204 |
| Zonulin upregulation is associated with increased gut permeability in subjects with type 1 diabetes and their relatives |
Sapone A., et al. |
Diabetes |
May-2006 |
16644703 |
| tate of the art: IBD therapy and clinical trials in IBD |
Isaacs K.L., et al. |
Inflamm Bowel Dis |
Nov-2005 |
16254481 |
| Risk of celiac disease autoimmunity and timing of gluten introduction in the diet of infants at increased risk of disease |
Norris J.M., et al. |
JAMA |
May-2005 |
15900004 |
| Association of celiac disease and intestinal lymphomas and other cancers |
Catassi C., et al. |
Gastroenterology |
Apr-2005 |
15825131 |
| Clinical features and diagnosis of celiac disease |
Dewar D.H., et al. |
Gastroenterology |
Apr-2005 |
15825122 |
| Celiac disease in patients with an affected member, type 1 diabetes, iron-deficiency, or osteoporosis? |
Murray J.A. |
Gastroenterology |
Apr-2005 |
15825127 |
| National Institutes of Health Consensus Development Conference Statement on Celiac Disease, June 28-30, 2004 |
James S.P. |
Gastroenterology |
Apr-2005 |
15825115 |
| The G.U.T. of gut |
Bjarnason I., et al. |
Scand J Gastroenterol |
Sep-2004 |
15513377 |
| Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences |
Loftus E.V. |
Gastroenterology |
May-2004 |
15168363 |
| Timing of initial cereal exposure in infancy and risk of islet autoimmunity |
Norris J.M., et al. |
JAMA |
Oct-2003 |
14519705 |
| Early infant feeding and risk of developing type 1 diabetes-associated autoantibodies |
Ziegler A.G., et al. |
JAMA |
Oct-2003 |
14519706 |
| Celiac disease–how to handle a clinical chameleon |
Fasano A. |
NEJM |
Jun-2003 |
12815143 |
| Title |
Author |
Journal |
Date |
PubMed ID |
| A prospective, double-blind, placebo-controlled trial to establish a safe gluten threshold for patients with celiac disease |
Catassi C., et al. |
Am J Clin Nutr |
Jan-2007 |
17209192 |
| Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines |
Drago S., et al. |
Scand J Gastroenterol |
Apr-2006 |
16635908 |
| Integrating theories of the etiology of Crohn’s disease. On the etiology of Crohn’s disease: questioning the hypotheses. |
Chamberlin W.M., et al. |
Med Sci Monit |
Feb-2006 |
16449960 |
| Gliadin stimulation of murine macrophage inflammatory gene expression and intestinal permeability are MyD88-dependent: role of the innate immune response in Celiac |
Thomas K.E., et al. |
J Immunol |
Feb-2006 |
16456012 |
| Clinical features and diagnosis of celiac disease |
Dewar D.H., et al. |
Gastroenterology |
Apr-2005 |
15825122 |
| The safe threshold for gluten contamination in gluten-free products. Can trace amounts be accepted in the treatment of coeliac disease? |
Collin P., et al. |
Aliment Pharmacol Ther |
Jun-2004 |
15191509 |
| Sourdough bread made from wheat and nontoxic flours and started with selected lactobacilli is tolerated in celiac sprue patients |
Di Cagno R., et al. |
Appl Environ Microbiol |
Feb-2004 |
14766592 |
| Environmental factors in the etiology of type 1 diabetes |
Akerblom H.K., et al. |
Am J Med Genet |
May-2002 |
12116173 |
| Environmental triggers of type 1 diabetes |
Couper J.J. |
J Paediatr Child Health |
Jun-2001 |
11474705 |
| Zonula occludens toxin structure-function analysis. Identification of the fragment biologically active on tight junctions and of the zonulin receptor binding domain |
Di Pierro M., et al. |
J Biol Chem |
Jun-2001 |
11278543 |
| Current concepts of celiac disease pathogenesis |
Schuppan D. |
Gastroenterology |
Jul-2000 |
10889174 |
| Vibrio cholerae produces a second enterotoxin, which affects intestinal tight junctions |
Fasano A., et al. |
Proc Natl Acad Sci U S A |
Jun-1991 |
2052603 |
| Dietary proteins as environmental modifiers of type 1 diabetes mellitus |
Lefebvre D.E., et al. |
Annu Rev Nutr |
Jun-1905 |
16848704 |
| Regulation of intercellular tight junctions by zonula occludens toxin and its eukaryotic analogue zonulin |
Fasano A. |
Ann N Y Acad Sci |
Jun-1905 |
11193578 |
